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DICHLORORIBOFURANOSYLBENZIMIDAZOLE
Inhibits selectively and reversibly the synthesis of two-thirds of nuclearheterogeneousRNA and approximately 95% of mRNA. Drb can markedly magnifyinterferon manufacture by poly I-c-induced human fibroblasts. It is used as a tool in the learn of intracellular mechanisms.
Pharmacological action: nucleic acid synthesis inhibitors.
Chemical name: 1H-Benzimidazole, 5,6-dichloro-1-beta-D-ribofuranosyl-