Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

NIDOGEN

A dumbbell shaped 150 kD sulphated glycoprotein that is found in all basement membranes. It binds to laminin, forming a very stable 1:1 composite (KD = 10nM) and nearly all laminin preparations contain entactin. The N terminal globular domain can self aggregate, whilst the C terminal globular domain binds to the short hand of laminin and to collagen IV. The connecting rod has 5-6 EGF type cysteine wealthy repeats, one of which has an RGD sequence for cellular interaction. This entry appears with alow from the Vocabulary of Cell and Molecular Biology
neological   neologism   neologist   neologistical   neology   neomembrane   neomenoidea   neomorph   (0)
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