An
experimental malady in rats, swine, turkeys, and another animals fed the
seeds of determined
species of Lathyrus (e.g., L. Odouratus, sweet pea), or such
nitriles as
aminoacetonitrile or beta-aminopropionitrile; the chief
pathologic changes occur in
connective tissue structures, as follows: 1) fibroblastic, chondroblastic, and
osteoblastic proliferative changes in the periosteum; 2) degeneration, necrosis, and
atypical proliferation of
epiphysial cartilages; 3) an
magnify in
adipose tissue of the
bone marrow; 4) sometimes proliferation of synovial membranes; 5) relatively
big foci of extensive destruction of
elastic fibres in the aorta, especially in the
thoracic aorta.
Origin: osteo-+ lathyrism