Glossary of Medical Terms

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ASSAM FEVER

A chronic malady, occurring in India, Assam, China, the area formerly known as the Mediterranean littoral areas, the Medium East, India, Pakistan, China, South and Central America, Asia, Africa caused by Leishmania donovani and transmitted by the bite of an appropriate species of sandfly of the genus Phlebotomus or Lutzomyia; the organisms grow and multiply in macrophages, eventually causing them to burst and liberate amastigote parasites which then invade another macrophages; proliferation of macrophages in the bone marrow causes crowding out of erythroid and myeloid elements, resulting in leukopenia, and anaemia, splenomegaly, and hepatomegaly which are quality, along with enlargement of lymph nodes; fever, fatigue, malaise, and secondary infections also occur; various strains of leishmaniasis donovani occur; leishmaniasis infantum in Eurasia, leishmaniasis chagasi in Latin America. Synonym: Assam fever, black sickness, Burdwan fever, cachectic fever, Dumdum fever, kala azar, tropical splenomegaly.
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