of steroids comprising the bile
acids (or salts), usually in conjugated form
acids). Chemically, cholic
acids are cholan-24-oic (cholanic) acids (the terminal
C24 of cholane
becoming a -COOH group); biologically, cholic
acids are derived from cholesterol
derivative) and display varying
degrees of oxidation
(OH groups) and orientation
at positions 3, 7, and 12. It is these oxidations and orientations that distinguish
the different cholic
acid; e.g., cholic acid
is 3a,7a,12a-trihydroxy-5b-cholan-24-oic acid, deoxycholic acid
is 3a,12a-dihydroxy-5b-cholanic acid.
Synonym: cholalic acid, cholanic acid.