Glossary of Medical Terms

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CREUTZFELDT-JAKOB SYNDROME

A rare, generally fatal, transmissible encephalopathy occurring in medium life, in which there is partial degeneration of the pyramidal and extrapyramidal systems accompanied by progressive dementia and sometimes muscle wasting, tremor, athetosis, and spastic dysarthria. A familial form has been shown to exhibit autosomal dominant inheritance. The more general sporadic form is perhaps caused by mutations that manufacture emergency prion proteins (prions). A variant of cjd has been reported in patients younger than 30 years old, perhaps caused by exposure to beef harboring the bovine spongiform encephalopathy agent.
romanizer   Romano, C   Romanovsky type stain   Romano-Ward syndrome   Romanowsky, Dimitri   Romanowsky's blood stain   romansch   romant   (0)
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