Glossary of Medical Terms

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DISSEMINATED CUTANEOUS LEISHMANIASIS

Leishmaniasis caused by different New and Old World species and strains of Leishmania (L. Mexicana amazonensis, L. M. Pifanoi, possibly L. M. Garnhami and L. M. Venezuelensis; in Ethiopia, L. Aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the non-ulcerating, non-necrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not appear to occur unless an acquired cellular hypersensitivity can develop. Synonym: anergic leishmaniasis, diffuse leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa, pseudolepromatous leishmaniasis.
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