Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

EXCISION REPAIR

Mechanism for the repair of environmental hurt to one strand of DNA (loss of purines due to thermal fluctuations, formation of pyrimidine dimers by UV irradiation). The site of hurt is recognised, excised by an endonuclease, the correct sequence is copied from the complementary strand by a polymerase and the ends of this correct sequence are joined to the rest of the strand by a ligase. The term is sometimes restricted to bacterial systems where the polymerase also acts as endonuclease.
heparinase   heparin binding growth factor   heparin cofactor II   heparin complement   heparin eliminase   heparin-glucosamine 3-O-sulfotransferase   heparinic acid   heparinise   (0)
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