Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

FINGERPRINTING

The basic principle of the technique is to digest a big molecule with a sequence specific hydrolase to manufacture temperate size fragments that can then be run on an electrophoresis gel. Provided the hydrolase only cleaves at specific sites (e.g. Between special amino acids or bases) then the fragments must be quality of that molecule. The technique can be used to distinguish strains of virus or to differentiate between similar but nonidentical proteins (peptide mapping). Not to be confused with footprinting. This entry appears with alow from the Vocabulary of Cell and Molecular Biology
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