Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

FUSION PROTEINS, BCR-ABL

Translation commodity of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukaemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukaemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in abelson murine leukaemia virus.
vegetative bacteriophage   vegetative endocarditis   vegetative fish cover   vegetative life   vegetative nervous system   vegetative pole   vegetative propagation   vegetative reproduction   (0)
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