Glossary of Medical Terms

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LYSOGENIC CONVERSION

The capacity of some phages to survive in a bacterium as a result of the integration of their DNA into the host chromosome. The integrated DNA is termed a prophage. A regulator gene produces a repressor protein that suppresses the lytic activity of the phage, but different environmental factors, such as ultraviolet irradiation may prevent synthesis of the repressor, leading to usual phage development and lysis of the bacterium. The excellent example of this is bacteriophage lambda. This entry appears with alow from the Vocabulary of Cell and Molecular Biology
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