Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

MACROPHAGE INFLAMMATORY PROTEIN

A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating haematopoiesis. Its two variants, mip-1alpha and mip-1beta, are 60% homologous to every other. They are heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory commodity of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They most likely also play a important role in respiratory tract defenses.
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