Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

OLIGONUCLEOTIDE PROBES

Synthetic or natural oligonucleotides used in hybridization research in order to designate and learn specific nucleic acid fragments, e.g., DNA segments around or within a specific gene locus or gene. The probe hybridises with a specific mRNA, if gift. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody trials. Conventional labels for the probe include the radioisotope labels 32p and 125i and the chemical label biotin.
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