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RIBONUCLEOPROTEINS, SMALL, U4-U6
A nuclear RNA-protein composite that plays a role in RNA processing. In the nucleoplasm, the u4-u6 snrnp along with the u5 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to formmature spliceosomes. There is also evidence for the subsistence of individual u4 or u6 snrnps in addition to their organization as a u4-u6 snrnp.