Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

THROMBOCYTOPENIA PURPURA

In severe thrombocytopenia, bleeding into skin leads to little petechial haemorrhages. Primary thrombocytopenia purpura is of unknown reason but results from an autoimmune mechanism that causes platelet destruction. Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus.
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