Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

THROMBOSIN

Protease (34 kD) generated in blood clotting that acts on fibrinogen to manufacture fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. This entry appears with alow from the Vocabulary of Cell and Molecular Biology
peroral endoscopy   per orally   per os   perosis   perosplanchnia   perosseous   peroxi-   peroxidase   (1)
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