Glossary of Medical Terms

Our online medical glossary of medical terms and definitions includes definitions for terms related to treatment, and general medicine

VH AND VL GENES/DOMAINS

VH and VL genes define in part the sequences of the variable hard and easy regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the hard chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures. This entry appears with alow from the Vocabulary of Cell and Molecular Biology
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